From I-95: Travel to the Port Orange exit on I-95 (exit #256). Take SR-421 east toward Port Orange. Continue east on SR-421 (Dunlawton Avenue) across the Halifax River to Atlantic Avenue. Turn right onto South Atlantic Avenue and travel five miles to the Town of Ponce Inlet. Turn right onto Lighthouse Drive. The Marine Science Center will be on the right.

From Daytona Beach: Travel south on South Atlantic Avenue to the Town of Ponce Inlet. Turn right onto Lighthouse Drive. The Marine Science Center will be on the right.

The Marine Science Center has a small parking lot off Lighthouse Drive; overflow parking is on Lighthouse Drive on the south side of the road.

facility map that shows marine science center, seabird rehabilitation sanctuary, nature trail, boardwalk, and observation tower